LONGBOARD LIFE

We are committed to improving the quality of life for individuals with devastating neurological conditions and strive to be the best possible teammates and colleagues. We are looking for people to join our team who are just as dynamic, talented, and passionate as we are.

Our Mission

We are committed to transforming the lives of patients, families, and caregivers impacted by neurological and rare diseases.

Our Vision

A world where devastating neurological conditions are no longer devastating.

Our Values

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Open Positions

Longboard Pharmaceuticals is an equal-opportunity employer offering competitive benefits. Our open positions are listed below. To apply, please send your CV to [email protected] with the position you are applying for in the subject line.

If the position you are looking for is not listed, please check back frequently for new open positions as our team is growing rapidly.

Job Title: Scientist/Principal Scientist
Reports To: Vice President, Translational Science
Department: R&D: Translational Science
Department Code: 3215
People Manager: No
FLSA Status: Exempt
Location: San Diego, CA- Hybrid or Remote

Summary

We are seeking a highly motivated and experienced Scientist to support our translational science team. The ideal candidate will have a strong background in scientific research in Neuroscience. This individual will be working within our programs in epilepsy and neuroinflammation and identify new opportunities for our growing pipeline.

Responsibilities

  • Conduct studies and address scientific issues relevant to Longboard’s development pipeline
  • Ensure that projects are completed on time, within budget, and to the highest quality standards
  • Collaborate with internal stakeholders and manage contract research
  • Actively participate in scientific conferences and other scientific meetings
  • Continuously review the latest scientific literature to identify new areas of research and potential collaborations
  • Contribute to IND/CTA submissions, Investigator Brochures, DSURs, and other regulatory submissions as needed
  • Additional job responsibilities and/or duties, as assigned

Qualifications

  • Ph.D. in Neuroscience, Pharmacology, or Biological Sciences
  • 1 to 3 years of post-doctoral experience in Neuroscience research
  • Strong knowledge of experimental design, data analysis, and statistical methods
  • Excellent communication skills, including the ability to effectively communicate complex scientific concepts to a non-scientific audience
  • Strong organizational skills and attention to detail
  • Ability to work independently and as part of a team
  • Knowledge of regulatory requirements and ethical standards in research

Preferred Qualifications

  • Experience in translational research in neurology and rare diseases, including epilepsy and neurodegenerative diseases
  • A strong publication record
  • Experience in managing complex research projects within an academic or industry environment
  • Experience working with industry partners and vendors
  • Strongly prefer San Diego area candidate for hybrid schedule

“Pay Transparency”

The salary range for candidates who work in La, Jolla, CA is $115-136k. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the industry, education, etc. Longboard Pharmaceuticals, Inc is a multi-state employer and will consider candidates based in remote work locations.

“Benefits”

Employees (and their families) are eligible for medical, dental, vision, and basic life insurance. Employees can enroll in our company’s 401k plan which currently includes matching up to 4% of earnings to IRS limits. Employees are also eligible for unlimited paid time off. Employees also currently enjoy paid time off for federal holidays and company closures for a week in August and a week in December each year. Benefits are subject to change.

“Other compensation”

Hired applicants will be granted stock options and may be eligible for annual bonuses.

If you are an enthusiastic and driven individual with a passion for translational science and drug discovery, we encourage you to apply for this exciting opportunity. We offer a competitive salary, a comprehensive benefits package, and a dynamic and collaborative work environment.

TO APPLY PLEASE CLICK ON THE FOLLOWING LINK:

Scientist/Principal Scientist – Longboard Pharmaceuticals, Inc. – Career Page (applytojob.com)

Job Title: Director, ADME
Reports To: V.P., Nonclinical Development
Department: R&D Nonclinical Development
Depart Code: 4105
People Manager: No
FSLA Status: Exempt
Location: Remote or La Jolla, CA

Summary

The Director of ADME will design, oversee, manage, and interpret nonclinical in vitro and in vivo ADME studies to support the development of compounds in Longboard’s development pipeline. The Director of ADME will possess deep knowledge and expertise in metabolism and pharmacokinetics with the ability to identify and follow up on issues that may present a hurdle to clinical development and/or affect human safety. The incumbent will play a pivotal role on cross-functional teams, and author and edit regulatory documents.

Responsibilities

  • Hands-on study design, study management, data analysis, and presentation for nonclinical studies are required to support development activities.
  • Represent ADME as the subject matter expert for nonclinical development.
  • Support programs at different stages with in vitro metabolism and in vivo ADME studies to ensure a complete understanding of the metabolism, tissue uptake/distribution, excretion profiles of drug candidates across species, and potential drug-drug interactions.
  • Conceive of and develop strategic plans for metabolite identification and characterization.
  • Deliver the preclinical and translational DMPK work package to support projects in lead optimization and clinical candidate selection.
  • Perform human PK projection and contribute to the analysis of preclinical PK/PD data for the selection of FIH dose levels.
  • Lead and prepare DMPK components of preclinical and clinical study protocol designs, nonclinical and clinical study reports, and investigator brochures.
  • Collaborate with Clinical Development to characterize human pharmacokinetics, metabolism, and biopharmaceutics of clinical compounds.
  • Partner with other departments as needed to advance drug development.
  • Author and edit key pre-clinical and regulatory documents including study protocols and reports, investigator brochures, IND/IMPDs, CTAs and NDAs within agreed timelines.
  • Monitor timelines, objectives, and budgets.
  • Ensure rapid and effective communication of high-quality data and results to project teams.
  • Manage junior team members.
  • Other duties as assigned.

Qualifications

  • Ph.D. in Chemistry, Pharmacology, Pharmacy, or related field required.
  • 10+ years of industry experience with particular experience in regulated drug development.
  • Small molecule drug development experience across multiple therapeutic areas including central nervous system disorders is strongly preferred.
  • Strong knowledge of ADME concepts, pharmacokinetic modeling, and pharmacodynamic and bioanalytical principles.
  • Deep expertise in metabolism, metabolic pathway identification, and knowledge of regulatory guidance and work streams related to metabolite characterization.
  • Strong strategic understanding of the appropriate timing of studies and data needed to enable relevant stage of clinical development.
  • Working knowledge of pharmacokinetic and other analysis software (e.g., WinNonlin, NONMEM, etc.) and demonstrated ability to plan, organize, and critically assess and/or perform PK/PD data analysis.
  • Expertise in developing, validating, and troubleshooting bioanalytical methods for various matrices.
  • Experience working with multiple national and international CROs.
  • Experience in authoring regulatory submissions and preparing detailed science-based responses to regulatory questions.
  • Working knowledge of CMC and product quality, to enable impurity assessment and justification of specifications.
  • Ability to manage multiple work streams and projects concurrently.
  • Ability to problem-solve, research issues, and propose solutions.
  • Excellent interpersonal and communication skills, both written and oral, and the ability to communicate complex information succinctly.
  • Effective and constructive collaborator.
  • Ability to function independently in a fast-paced, virtual environment.
  • Strong working knowledge of GxP, FDA, and ex-US regulatory requirements for the conduct of nonclinical safety studies to support regulatory filings.

“Pay Transparency”

The salary range for candidates who work in La, Jolla, CA is $197-243k. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the industry, education, etc. Longboard Pharmaceuticals, Inc is a multi-state employer and will consider candidates based in remote work locations.

“Benefits”

Employees (and their families) are eligible for medical, dental, vision, and basic life insurance. Employees can enroll in our company’s 401k plan which currently includes matching up to 4% of earnings to IRS limits. Employees are also eligible for unlimited paid time off. Employees also currently enjoy paid time off for federal holidays and company closures for a week in August and a week in December each year. Benefits are subject to change.

“Other compensation”

Hired applicants will be granted stock options and may be eligible for annual bonuses.

TO APPLY PLEASE CLICK ON THE FOLLOWING LINK:

Director, ADME – Longboard Pharmaceuticals, Inc. – Career Page (applytojob.com)

At Longboard, we believe benefits are an important part of our employees’ overall compensation and well-being. We are pleased to offer a comprehensive array of valuable benefits to protect the health of our employees, their families and their way of life.

Our benefits currently include:

  • Medical Plan (90% of premium paid by company)
  • Dental Plan (90% of premium paid by company)
  • Vision Plan (90% of premium paid by company)
  • Life and AD&D (no cost to employee for basic coverage)
  • Short-Term Disability – Long-Term Disability – Cost of Benefits
  • 401(k) Plan, including company match with immediate vesting
  • Paid Time Off, including one week off in the summer and one week off around December holidays
  • Longboard Perks (gym, garage parking, company-sponsored events, etc.)

Our Employees

“I was really excited to join Kevin early on at Longboard where we are focused on improving the lives of patients with devastating neurological conditions. We are building a team that is passionate and talented, as well as fun, diverse and inclusive. With team members across the United States, we foster an environment of collaboration where we thrive together, challenge each other to do better and strive to make a difference in each other’s lives as well as the lives of patients.”

Brandi Roberts
Chief Financial Officer

“At Longboard we are creating a culture that values different opinions and approaches to problem solving with an open collaboration across all levels of the organization. I am thrilled to join the company at an early stage so I can openly engage with every employee to learn what motivates them and to help them to succeed and enjoy their journey with Longboard.”

Jennifer Patterson
Director, Human Resources

Live the
Longboard Life.

We are committed to improving the quality of life for individuals with devastating neurological conditions and strive to be the best possible teammates and colleagues. Learn more about our culture, benefits and open positions.

We show up
for patients.

The people living with, supporting and treating those with neurological conditions are at the center of what we do. Learn more about our commitment.