LONGBOARD LIFE
We are committed to improving the quality of life for individuals with devastating neurological conditions. Our team works together to create a company culture and welcoming environment we are proud to be a part of. We are looking for dynamic, talented, and passionate people to join our team.
View open positions here
Life at Longboard
Our Mission
We are committed to transforming the lives of patients, families, and caregivers impacted by neurological and rare diseases.
Our Vision
A world where devastating neurological conditions are no longer devastating.
Our Values
Open Positions
Longboard Pharmaceuticals is an equal-opportunity employer offering a competitive benefit package. Our open positions are listed below. To apply, please click on the position of interest.
If the position you are looking for is not listed, please check back in the future.
Reports To: Director, Clinical Line Management
Department: R&D: Clinical Operations
People Manager: No
FLSA Status: Exempt
Location: San Diego, CA
Schedule: Hybrid (2-3 days a week) out of San Diego office
Position Summary
The Clinical Research Associate (CRA) supports global and regional clinical trial managers and trial leaders in the planning, designing, executing, monitoring, and reporting of clinical trials. The In-House Clinical Research Associate partners with internal and external team members/key stakeholders ensuring alignment of activities with study projects and timelines to include, but not limited to, essential document collection and review; investigative site recruitment & feasibility; FDA/GCP/ICH and regulatory compliance; data management and query resolution; document and SOP review; study document/plan development and review; maintenance and close-out of in-house site management activities; and clinical operations support activities and tasks.
Responsibilities include but may not be limited to:
- Supports the global and regional clinical trial managers and trial leaders in the planning, execution, and reporting of clinical trials, ensuring alignment of activities with study timelines, budgets, SOPs, GCP, and applicable regulatory guidelines
- Performs an array of assigned duties including investigator site recruitment/feasibility; essential document collection and review; ICF review; study document/plan development and review; maintenance and close-out of in-house site management activities in accordance with the protocol; review and compliance with standard operating procedures (SOPs); ICH/GCP guidelines and all applicable regulatory requirements
- Assists in the review and approval of monitoring reports
- May conduct co-monitoring or observational visits at investigational sites
- Assists with the preparation and finalization of investigators’ contracts, budgets, and payments
- Obtain, review (to ensure completeness, accuracy, and regulatory compliance), and process essential regulatory, and administrative documents, and Informed Consent Forms (ICFs)
- Works with Technical Operations and/or CTAs to Initiate investigational product shipments as needed and ensures that supplies are adequate/appropriate for assigned studies and sites
- Interacts with other functional areas and key stakeholders, including Clinical Development, Data Management, Finance, Regulatory, Quality Assurance, Safety, Clinical Supply (Investigational Product), and clinical vendors (e.g., central laboratory, CROs), as needed, to support clinical trial activities
- Ongoing interaction with clinical operations team members and Investigator site staff to obtain and relay key study issues, status updates, and other study information to the clinical trial team and management
- Participates in the development and improvement of department processes, best practices, and tools and templates related to clinical trial management and operations
- Participates in the review and development of CRFs and CRF guidelines
- Performs in-house review of CRF data for completeness and accuracy, and resolves data management/query issues with study sites and vendors as needed
- Reviews data to identify protocol deviations and risks to subject safety/data integrity
- Works with CTAs to obtain licensing for study tools and assessments
- Evaluates the execution of the study protocol at the site level. Uses judgment and experience to evaluate the overall performance of site and site staff to provide recommendations regarding site-specific actions; immediately communicates/escalate serious issues to the study team
- Work with assigned CTAs and CROs to ensure study activities are documented via confirmation letters, follow-up letters, trip reports, communication logs, and other required study documents as per SOPs and the Study Monitoring Plan
- Supports and monitors clinical trials to ensure sponsor and investigator obligations are met and in compliance with the currently approved protocol/amendment(s); applicable study procedures; applicable federal and local regulatory requirements; GCP; and company policy and procedures
- Supports the oversight of all activities listed and ensures all duties/documents/protocols/etc. meet Longboard’s expectations, and delivers them in accordance with the sponsor’s expectations, trial protocol, ICH/GCP guidelines, and applicable SOPs (local/US/international)
- Verifies that the rights and well-being of human subjects are protected and that the reported trial data are accurate, complete, and verifiable from source documents
- Performs other work-related duties as assigned or required
Minimum Requirements
- Bachelor’s degree, preferred
- 5+ years of relevant and progressive experience with clinical trials
- Experience in all stages of clinical trial conduct (study start-up, maintenance, database lock, etc.) and a strong understanding of clinical trial processes, protocols, and medical terminology
- Prior experience in management and monitoring of CRO and investigative sites, preferred
- Experience with patient recruitment, non-compliance, safety, document management, an investigational product, IP accountability
- Strong written and verbal communication and computer literacy (e.g., Microsoft Word, Excel, PowerPoint, Outlook); strong experience utilizing CTMS, EDC, TMS, and related software
- Knowledge of ICH GCP, IRB/IEC, and local regulatory authority drug research & development regulations
- Motivated to work in a fast-paced, high-accountability environment
- Experience with bio-samples, storage of 3rd party data, and preferred
- Experience in Longboard’s focused therapeutic areas, preferred
- Travel up to 35%
About Longboard
At Longboard Pharmaceuticals, our mission is to enhance the lives of individuals battling profound neurological conditions. Collaboratively, we foster an inclusive company culture and an inviting environment that we take immense pride in. We actively seek dynamic, talented, and dedicated individuals to join our team.
Pay Transparency
The expected salary for candidates who work in La, Jolla, CA is $130,000.00 – $150,000.00. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the industry, education, etc. Longboard Pharmaceuticals, Inc is a multi-state employer and will consider candidates based in remote work locations.
Benefits
At Longboard, we prioritize the well-being and satisfaction of our employees, understanding that benefits play a crucial role in their overall compensation and life quality. We take pride in providing a robust suite of benefits designed to safeguard the health and happiness of our team members, their families, and their lifestyles.
Our benefits currently include:
- Hybrid work schedule out of our La Jolla office, 2-3 days a week
- Competitive compensation package including bonus opportunities and stock options
- Medical, Dental & Vision Plans
- 401(k) Plan, including company match with immediate vesting
- Flexible Time Off, including one week off in the summer and one week off around December holidays
- 11 paid company holidays per year
- An opportunity to do truly meaningful work to make a lasting impact
- Longboard Perks (on-site gym, garage parking, company-sponsored events, etc.)
- Flexible spending account for medical care
- Life insurance, short and long term disability plans
TO APPLY PLEASE CLICK ON THE FOLLOWING LINK:
Reports To: VP, Head of Clinical Operations
Department: R&D Clinical Operations
People Manager: No
FLSA Status: Exempt
Location: San Diego, CA
Schedule: Hybrid (2-3 days a week) out of San Diego office
Position Summary
The Clinical Trial Assistant (CTA) supports study teams in the planning, designing, executing, monitoring, and reporting of clinical trials. The CTA acts as a partner for internal and external team members/key stakeholders ensuring alignment of activities with study projects and timelines. The CTA, under the direction and guidance of the VP, Head of Clinical Operations will work independently but knows when to involve and/or collaborate with other functional members when needed.
Responsibilities include but may not be limited to:
- Supports study teams as necessary to complete all study activities
- Responsible for accurate and complete filing of all key documentation into the eTMF
- Supports team in completing site documentation (CDAs, Contracts, Licenses, 1572s, CVs, Financial Disclosure forms, etc.)
- Participate in Site Visits with experienced GCTL or CRA (site monitoring/engagement visits)
- Supports logistics and development of materials for Investigator Site meetings
- Maintains minutes for assigned meetings
- Prioritizes and plans work activities; Uses time efficiently to meet deadlines
Minimum Requirements
- Bachelor’s degree, preferred
- 2+ years’ experience as a Clinical Trial Assistant in life sciences industry preferred
- Understanding of Good Clinical Practices
- Strong written and verbal communication skills
- Proficient in Microsoft suite of products; Microsoft Word, Excel, PowerPoint, Outlook
- Experience utilizing CTMS, EDC, TMS, and related software preferred
- Attention to detail, and excellent organizational and prioritization skills
- Motivated to work in a fast-paced, high-accountability environment
- Ability to efficiently perform multiple tasks and manage changing priorities
- Open to 25% travel
About Longboard
At Longboard Pharmaceuticals, our mission is to enhance the lives of individuals battling profound neurological conditions. Collaboratively, we foster an inclusive company culture and an inviting environment that we take immense pride in. We actively seek dynamic, talented, and dedicated individuals to join our team.
Pay Transparency
The expected salary for candidates who work in La, Jolla, CA is $100,000.00 – $125,000.00. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the industry, education, etc. Longboard Pharmaceuticals, Inc is a multi-state employer and will consider candidates based in remote work locations.
Benefits
At Longboard, we prioritize the well-being and satisfaction of our employees, understanding that benefits play a crucial role in their overall compensation and life quality. We take pride in providing a robust suite of benefits designed to safeguard the health and happiness of our team members, their families, and their lifestyles.
Our benefits currently include:
- Hybrid work schedule out of our La Jolla office, 2-3 days a week
- Competitive compensation package including bonus opportunities and stock options
- Medical, Dental & Vision Plans
- 401(k) Plan, including company match with immediate vesting
- Flexible Time Off, including one week off in the summer and one week off around December holidays
- 11 paid company holidays per year
- An opportunity to do truly meaningful work to make a lasting impact
- Longboard Perks (on-site gym, garage parking, company-sponsored events, etc.)
- Flexible spending account for medical care
- Life insurance, short and long term disability plans
TO APPLY PLEASE CLICK ON THE FOLLOWING LINK:
Clinical Trial Assistant (CTA) – Longboard Pharmaceuticals, Inc. – Career Page (applytojob.com)
Job Title: Senior Manager, Accounting
Reports To: Controller
Department: Finance
People Manager: Yes
FLSA Status: Exempt
Location: San Diego, CA
Schedule: Hybrid, in office 2-3 days a week
Position Summary
Reporting to the Controller, the Senior Manager, Accounting will be responsible for the timely and accurate preparation of financial accounting data, and for the daily management of accounting functions and processes for the company. The Senior Manager, Accounting needs to collaborate effectively with people in all departments and at all levels within the organization.
Responsibilities
- Provide leadership to team members and ensure a high level of performance, productivity, and integrity
- Demonstrate strong leadership skills in fostering a positive and collaborative team environment
- Lead month-end closing activities; prepare or review all journal entries, including complex journal entries for clinical, preclinical, and manufacturing expenses, allocations and global consolidation
- Prepare/review balance sheet account reconciliations on a monthly basis; reconcile complex balance sheet accounts and investigate/resolve variances
- Prepare financial reporting package (income statement, balance sheet, statement of cash flows, statement of shareholders’ equity, and financial statement analysis) for internal and external reporting
- Responsible for bi-monthly payroll processing
- Review weekly check runs and ensure the timely payment of invoices; review all invoices for coding
- Preparation of equity-related journal entries, administration of equity awards and reconciliation of equity award activity
- Assist the controller with the annual audit process, including the preparation of audit schedules and interaction with external auditors
- Assist in the preparation of support schedules needed for the annual tax provision/return
- Assist the controller with the implementation of Sarbanes-Oxley (SOX) systems and processes, including documentation of policies, procedures, and controls
- Assist with SOX 404b audit activities, as applicable
- Assist the controller with any accounting-related efficiency projects, such as new tool implementations
Minimum Qualifications
- Bachelor’s degree in Accounting, Finance, or related field
- CPA preferred
- Minimum of 7 years’ accounting experience in a business setting, with at least 3 years in a managerial role
- Experience within the life science industry required
- Previous experience with accounting in a publicly traded company required
- Significant Sarbanes Oxley compliance experience, 404b experience preferred
- Stock option administration and Equity Edge / E*TRADE experience preferred
- Knowledge of GAAP accounting, financial statements, budgeting and forecasting, cash flows, and auditing
- Experience with global operations and consolidations preferred
- Prior experience in managing team members, including the ability to provide guidance, support and clear direction
- Excellent written and verbal communication skills, along with the ability to present numeric data effectively
- Exceptional listening, observational and problem-solving skills
- Exceptional time-management abilities and strong follow-through skills required
- Experience managing confidential information
- Experience working in a fast-paced environment handling a wide range of tasks with little supervision or oversite required
- Friendly, team-oriented, collaborative, and “can-do” attitude
- Intermediate-to-advanced computer and MS Office skills (Outlook/Word/Excel/PowerPoint); Experience with conference equipment/platforms
About Longboard
At Longboard Pharmaceuticals, our mission is to enhance the lives of individuals battling profound neurological conditions. Collaboratively, we foster an inclusive company culture and an inviting environment that we take immense pride in. We actively seek dynamic, talented, and dedicated individuals to join our team.
Pay Transparency
The expected salary for candidates who work in La, Jolla, CA is $140,000-160,000. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the industry, education, etc. Longboard Pharmaceuticals, Inc is a multi-state employer and will consider candidates based in remote work locations.
Benefits
At Longboard, we prioritize the well-being and satisfaction of our employees, understanding that benefits play a crucial role in their overall compensation and life quality. We take pride in providing a robust suite of benefits designed to safeguard the health and happiness of our team members, their families, and their lifestyles.
Our benefits currently include:
- Hybrid work schedule out of our La Jolla office, 2-3 days a week
- Competitive compensation package including bonus opportunities and stock options
- Medical, Dental & Vision Plans
- 401(k) Plan, including company match with immediate vesting
- Flexible Time Off, including one week off in the summer and one week off around December holidays
- 11 paid company holidays per year
- An opportunity to do truly meaningful work to make a lasting impact
- Longboard Perks (on-site gym, garage parking, company-sponsored events, etc.)
- Flexible spending account for medical care
- Life insurance, short and long term disability plans
TO APPLY PLEASE CLICK ON THE FOLLOWING LINK:
Senior Manager, Accounting – Longboard Pharmaceuticals, Inc. – Career Page (applytojob.com)
Job Title: Vice President, Clinical Development
Reporting To: CMO
Department: R&D Management
People Manager: Yes
FLSA Status: Exempt
Location: La Jolla, CA
Company Background
Longboard Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company focused on developing novel, transformative medicines for neurological diseases. Longboard is working to advance a portfolio of centrally acting product candidates designed to be highly selective for specific G protein-coupled receptors (GPCRs). Longboard’s small molecule product candidates are based on more than 20 years of GPCR research. Longboard plans to advance bexicaserin (LP352), an oral, centrally acting 5-hydroxytryptamine 2C (5-HT2C) receptor superagonist, with no observed impact on 5-HT2B and 5-HT2A receptor subtypes, into a global Phase 3 program. In January 2024, Longboard reported topline data from a Phase 1b/2a clinical trial, the PACIFIC Study, evaluating bexicaserin in participants ages 12 to 65 years old with a broad range of Developmental and Epileptic Encephalopathies (DEEs), including Lennox-Gastaut syndrome, Dravet syndrome and other DEEs. “These exciting PACIFIC Study results underscore our belief that bexicaserin’s differentiated profile will translate into a clinically and commercially best-in-class product and has the potential to redefine the standard of care in DEEs. We are pleased to see such strong seizure reduction across a wide range of DEE syndromes with varying etiologies coupled with favorable safety and tolerability results,” stated Dr. Randall Kaye, Longboard’s Chief Medical Officer. “We would like to thank the entire DEE community, including study participants, their caregivers and advocacy groups, as well as the investigators, sites and coordinators for their participation and continued partnership as we advance into a Phase 3 program. This tremendous milestone brings us one step closer to improving the lives of those living with these devastating diseases and their families.”
Longboard is also evaluating LP659, an oral, centrally acting, sphingosine-1-phosphate (S1P) receptor subtypes 1 and 5 modulator, which is in development for the potential treatment of rare neuroinflammatory conditions. Longboard has initiated a Phase 1 single-ascending dose (SAD) clinical trial for LP659 in healthy volunteers, with topline data expected in the first half of 2024.
Position Summary
Reporting to the EVP/Chief Medical Officer, the Vice President, Clinical Development provides medical leadership for multiple small molecule programs. The Vice President is responsible for the development and execution of translational medicine and clinical development strategies including the design, implementation, monitoring, analysis, and reporting of clinical studies conducted within one or more programs. In addition, he/she/they collaborate with other team members and functions to develop long-range strategic plans for the programs and execute upon these plans.
Responsibilities include but may not be limited to:
- Lead and design translational medicine and clinical development strategies for one of more clinical programs.
- Lead activities related to phase 1-4 clinical trials (e.g., develop protocols, investigator brochures, and clinical study reports; review clinical trial documents, CRO management, clinical support of regulatory interaction, and study analysis and reporting).
- Partner with Biology and Biomarkers & Precision Medicine to development translational biomarker plans that are integrated into clinical trials
- Partner with Quality Assurance, Regulatory Affairs, and Project Management to ensure timely and effective clinical and scientific input into overall program.
- Lead investigator meetings and site initiation visits with clinical trial investigators, and partner with Clinical Operations in driving enrollment into the clinical studies
- Represent the company at scientific meetings, patient advocacy events and presentations, as well as other public relations opportunities, as directed by the CMO and Clinical Development
- Study Data Review and Analysis
- Provide clinical input into statistical planning and lead data analysis and interpretation
- Perform ongoing review and analysis of study data
- Provide medical leadership as needed for scientific issues that may arise during clinical trial execution
- Provide medical leadership and support for publication of data (e.g., manuscripts, posters) and disease or technology related scientific publications
- Build to scale a world class cross functional clinical development organization, upon the right inflection points and at a sensible cadence
- Define, plan and provide Medical Monitoring to clinical development studies
- Review adverse events, monitor safety, and prepare analysis and regulatory submission.
- Conduct thorough medical review of individual case safety reports (ICSRs)
Minimum Requirements
- Medical Degree required; experience in a relevant specialty such as Neurology, Pediatrics and/or Rare Diseases preferred.
- 7+ years biotechnology/pharmaceutical relevant experience leading clinical drug development (early-stage development through approval,) including developing clinical protocols, study design and successful regulatory approval (INDs, BLAs, NDAs) with US and international regulatory agencies
- Proven clinical development experience designing, implementing and conducting clinical trials
- A history of strong collaboration and personal interaction with all levels of internal stakeholders including, Regulatory Affairs, Clinical Operations, Research, and Product Development
- Understanding of global pharmacovigilance regulatory requirements and guidance documents and proven ability to influence decision making around multifaceted issues involving medical safety
- Outstanding leadership skills; comfortable working in a flexible, dynamically changing and challenging environment
- Excellent strategic planning, organizational and communication skills
- Highest level of scientific integrity
- Expertise and consistent success in scientific research and/or clinical practice, as evidenced by appropriate higher qualifications, publication and/or relevant specialist accreditation
- Strong computer skills including MS Office Suite (Word, Excel, PowerPoint, Outlook, MS Project) and in the use of industry-standard software (e.g., electronic data capture systems) and proficient in data analysis software and data presentation
- Willingness to travel ~25%, with international travel at times
Pay Transparency
The expected salary for candidates who work in La, Jolla, CA is $350-400k. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the industry, education, etc. Longboard Pharmaceuticals, Inc is a multi-state employer and will consider candidates based in remote work locations.
Benefits
At Longboard, we prioritize the well-being and satisfaction of our employees, understanding that benefits play a crucial role in their overall compensation and life quality. We take pride in providing a robust suite of benefits designed to safeguard the health and happiness of our team members, their families, and their lifestyles.
Our benefits currently include:
- Hybrid work schedule out of our La Jolla office, 2-3 days a week
- Competitive compensation package including bonus opportunities and stock options
- Medical, Dental & Vision Plans
- 401(k) Plan, including company match with immediate vesting
- Flexible Time Off, including one week off in the summer and one week off around December holidays
- 11 paid company holidays per year
- An opportunity to do truly meaningful work to make a lasting impact
- Longboard Perks (on-site gym, garage parking, company-sponsored events, etc.)
- Flexible spending account for medical care
- Life insurance, short and long term disability plans
TO APPLY PLEASE CLICK ON THE FOLLOWING LINK:
Job Title: Senior Scientist / Associate Director, Preclinical ADME
Reporting To: Senior Director, ADME
Department: R&D Nonclinical Development
People Manager: No
FLSA Status: Exempt
Location: Remote or hybrid (2-3 days a week) based in La Jolla, CA
Position Summary
The Senior Scientist / Associate Director, Preclinical ADME will be a member of the R & D Nonclinical Development Department and will contribute to the successful development, implementation, and execution of a non-clinical ADME drug discovery and development strategy that delivers decision-enabling quality data and meets the project timelines for Longboard’s R&D pipeline. You will be a company ADME/DMPK subject matter expert and will develop strong collaborative partnerships with the other functions such as medicinal chemistry, pharmacology, toxicology and clinical development. As such, extensive experience and expertise in small molecule ADME/DMPK is required as demonstrated by a proven track-record of optimizing lead molecules to NME selection and beyond, including accomplishment with successful small molecule regulatory interactions e.g., INDs and NDAs.
Responsibilities include but may not be limited to:
- Represent ADME in project teams with accountability for optimal design and execution of DMPK and PK/PD strategies from discovery to entry into human
- Be part of a team of DMPK experts to provide integrated screening and translational strategies to the Longboard portfolio
- Participate in study design, vendor selection, study execution, interpretation and report writing for molecules that pertain to PK and PK/PD assessment in research and development
- Serve as a key contributor to aid the selection and timely development of new drug candidates, through close interaction with therapeutic areas and affiliated non-clinical, clinical and regulatory functions
- Conduct PK/PD data analysis and modeling
- Initiate and facilitate collaborations with external partners, biology, and pharmacology colleagues in support of PKPD; outsource and manage ADME and DMPK studies at CROs
- Establish DMPK strategies that align with program goals and strive for high quality drug candidates
- Effectively communicate DMPK data and their relevance to multidisciplinary project teams, management, regulatory authorities, and potential partners
- Integrate knowledge and lead comprehensive investigations of all DMPK-PD related activities including strategic planning, designing of studies and data integration into phase transition and regulatory documents
- Prepare preclinical DMPK reports according to regulatory standards
- Work collaboratively in close partnership with disciplines such as medicinal chemistry, pharmacology, toxicology, pharmaceutical sciences, clinical pharmacology and regulatory to design promising clinical therapeutic candidates, flawlessly execute conduct of preclinical development studies, support clinical evaluation and contribute to IND and NDA filing
Minimum Requirements
- Ph.D. in pharmacokinetics, drug metabolism, or related discipline with a minimum of 5 years of relevant industrial experience in the evaluation of small molecule therapeutics
- Broad understanding of DMPK concepts and relevant areas such as physicochemical properties, drug metabolizing enzyme and transporter kinetics, pharmacokinetics, biotransformation and analytical sciences
- Broad understanding of drug discovery and development, especially as it relates to small molecules
- Broad understanding of PKPD concepts
- Hands-on modeling experience using Phoenix Winnonlin, Gastroplus, ADAPT or similar software
- Evidence of leadership in the DMPK field and a proven track record of scientific achievement and project influence, including ability to influence external scientific and regulatory practices through publication and other interactions
- Ability to multi-task in a fast-paced dynamic environment while demonstrating a calm and positive attitude and a superior work ethic
- Excellent verbal and written communication skills as well as strong interpersonal skills
- 15% travel required if remote to San Diego headquarters
Pay Transparency
The expected salary for candidates who work in La Jolla, CA is $180-198k. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the industry, education, etc. Longboard Pharmaceuticals, Inc is a multi-state employer and will consider candidates based in remote work locations.
Our benefits currently include:
- Hybrid work schedule out of our La Jolla office, 2-3 days a week
- Competitive compensation package including bonus opportunities and stock options
- Medical, Dental & Vision Plans
- 401(k) Plan, including company match with immediate vesting
- Flexible Time Off, including one week off in the summer and one week off around December holidays
- 11 paid company holidays per year
- An opportunity to do truly meaningful work to make a lasting impact
- Longboard Perks (on-site gym, garage parking, company-sponsored events, etc.)
- Flexible spending account for medical care
- Life insurance, short and long term disability plans
TO APPLY PLEASE CLICK ON THE FOLLOWING LINK: